A dendrite is a part of a nerve cell in the brain and nervous system. Think of it like the branches of a tree. Dendrites receive signals from other nerve cells and help pass those signals to the main part of the nerve cell. They play a key role in helping nerve cells communicate with each other
Examples of the impact of dendrite function has on some mental health disorders:
- Depression:
- Research has shown that individuals with depression often have altered dendritic morphology. For instance, studies indicate reduced dendritic branching and spine density in certain brain regions, such as the prefrontal cortex and hippocampus, which are linked to mood regulation and cognitive functions.
- Schizophrenia:
- In schizophrenia, dendritic abnormalities have been observed, particularly in the prefrontal cortex and hippocampus. These abnormalities include reduced dendritic branching and spine density, which may contribute to the cognitive and emotional symptoms associated with the disorder.
- Alzheimer’s Disease:
- In Alzheimer’s disease, dendritic degeneration is a prominent feature. The loss of dendritic spines and synaptic connections in the brain contributes to cognitive decline and memory loss observed in the disease.